
The Original A2M
Leading the way in A2M Concentration

Discover Alpha2active™, Powered by Alpha-2-Macroglobulin (A2M)
A naturally occurring molecule found in the blood, Alpha-2-Macroglobulin (A2M) acts as a powerful protector against cartilage breakdown. Certain actions of the proteins in our body can damage the joints and cause inflammation, resulting in pain and a lower quality of life. So like a Venus flytrap, A2M is designed to capture those destructive enzymes and eliminate them through the body.
The A2M molecule is essentially your body’s own defense mechanism! Alpha2Active, formerly known as APIC-A2M, uses a patented filtration process to concentrate this powerful Miracle Molecule™.

A pioneer in precision
a2m concentration

The Power Behind ALPHA2ACTIVE™
This is the true story of a board-certified spine surgeon, Dr. Gaetano “Guy” Scuderi, who was determined to locate—and address—the source of pain after a life-altering motorcycle accident. But what began as a tragic moment on the road became the driving force behind a breakthrough that’s helping countless patients reclaim their lives.
After two broken hands, multiple surgeries, and relentless pain from his injuries, Dr. Scuderi realized there is a signifcant gap in this area.
Determined to bridge this gap, his research led to the discovery and enhancement of the natural restorative properties of Alpha-2-Macroglobulin (A2M).

“[ALPHA2ACTIVE™] works. Living the last six months, without pain, it reminds me of when I was 30 years younger! And I used my own body! What else can you ask for?”
63-year-old Patient | Melbourne, FL
